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v600e mutant kinase assay kit catalog number 48688  (BPS Bioscience)


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    Structured Review

    BPS Bioscience v600e mutant kinase assay kit catalog number 48688
    V600e Mutant Kinase Assay Kit Catalog Number 48688, supplied by BPS Bioscience, used in various techniques. Bioz Stars score: 93/100, based on 14 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/48688/BRAF+(V600E)+Kinase+Assay+Kit/us12459951-3066-2-13
    Average 93 stars, based on 14 article reviews
    v600e mutant kinase assay kit catalog number 48688 - by Bioz Stars, 2026-11
    93/100 stars

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    Related Articles

    In Vitro:

    Article Title: Design, synthesis, and evaluation of new benzimidazole‏ ‏‎thiourea ‎derivatives as antitumor agents.
    Article Snippet: Funding information None Abstract Novel benzimidazole thiourea derivatives were designed and synthesized based on sorafenib as a lead compound.. The benzimidazole moiety was traded by the pyridine ring to enhance the hydrophobic interaction and retain hydrogen bonding in the hinge region, while lipophilic moieties with different bulkiness were employed in the deep hydrophobic pocket for better hydrophobic interactions.. Thiourea as a urea bioisostere was also utilized.

    Enzyme Inhibition Assay:

    Article Title: Design, synthesis, and evaluation of new benzimidazole‏ ‏‎thiourea ‎derivatives as antitumor agents.
    Article Snippet: Funding information None Abstract Novel benzimidazole thiourea derivatives were designed and synthesized based on sorafenib as a lead compound.. The benzimidazole moiety was traded by the pyridine ring to enhance the hydrophobic interaction and retain hydrogen bonding in the hinge region, while lipophilic moieties with different bulkiness were employed in the deep hydrophobic pocket for better hydrophobic interactions.. Thiourea as a urea bioisostere was also utilized.

    Enzyme-linked Immunosorbent Assay:

    Article Title: Design, synthesis, and evaluation of new benzimidazole‏ ‏‎thiourea ‎derivatives as antitumor agents.
    Article Snippet: Funding information None Abstract Novel benzimidazole thiourea derivatives were designed and synthesized based on sorafenib as a lead compound.. The benzimidazole moiety was traded by the pyridine ring to enhance the hydrophobic interaction and retain hydrogen bonding in the hinge region, while lipophilic moieties with different bulkiness were employed in the deep hydrophobic pocket for better hydrophobic interactions.. Thiourea as a urea bioisostere was also utilized.

    Mutagenesis:

    Article Title: Compounds that interact with RAS superfamily proteins for treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease
    Article Snippet: Luminescence, integration time 1 second, was measured using a SpectraMax M3 (Molecular Devices, San Jose, California). .. The B-Raf (V600E mutant) Kinase Assay Kit (catalog number 48688) was purchased from BPS BioScience, San Diego, CA. ..

    Kinase Assay:

    Article Title: Compounds that interact with RAS superfamily proteins for treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease
    Article Snippet: Luminescence, integration time 1 second, was measured using a SpectraMax M3 (Molecular Devices, San Jose, California). .. The B-Raf (V600E mutant) Kinase Assay Kit (catalog number 48688) was purchased from BPS BioScience, San Diego, CA. ..

    Article Title: Novel 5,6-dichlorobenzimidazole derivatives as dual BRAF WT and BRAF V600E inhibitors: design, synthesis, anti-cancer activity and molecular dynamics simulations
    Article Snippet: .. Procedure The inhibitory activity against different kinases was determined using kinase kits (BRAFWT cat. ID: 78316) and (BRAFV600E cat. ID: 48688) were purchased from BPS Biosciences and kinaseGlo Max luminescence kinase assay kit (Promega). ..

    Article Title: Untargeted Diversity-Oriented Synthesis for the Discovery of New Antitumor Agents: An Integrated Approach of Inverse Virtual Screening, Bioinformatics, and Omics for Target Deconvolution
    Article Snippet: .. The B-Raf kinase assay (V600E; BPS Bioscience, USA) was designed to measure B-Raf kinase activity by the use of Kinase-Glo MAX (Promega, USA), which detects ATP residual following the kinase reaction. ..

    Article Title: Untargeted Diversity-Oriented Synthesis for the Discovery of New Antitumor Agents: An Integrated Approach of Inverse Virtual Screening, Bioinformatics, and Omics for Target Deconvolution
    Article Snippet: Poly [ADP-ribose] polymerase tankyrase-1 , TNKS1 (PARP5A) Colorimetric Assay Kit (BPS Bioscience, USA) , >30 , >30. .. serine/threonine-protein kinase B-raf , B-Raf kinase assay (V600E; BPS Bioscience, USA) , ≥30 , ≥30. .. cannabinoid receptor 1 , Binding assays evaluating the displacement of the high-affinity radioligand [ 3 H]-CP-55,940 (Perkinelmer, Italy) , >30 , >30.

    Article Title: Investigation into the Use of Encorafenib to Develop Potential PROTACs Directed against BRAF V600E Protein.
    Article Snippet: .. BRAFV600E Inhibition Assay Inhibition of B-RAF (V600E) Kinase activity by synthesized compounds was measured with a B-RAF (V600E) Kinase Assay Kit purchased from BPS Bioscience using Kinase-Glo MAX® (Promega Corporation, Madison, Wisconsin, USA) as detection reagent. ..

    Activity Assay:

    Article Title: Novel 5,6-dichlorobenzimidazole derivatives as dual BRAF WT and BRAF V600E inhibitors: design, synthesis, anti-cancer activity and molecular dynamics simulations
    Article Snippet: .. Procedure The inhibitory activity against different kinases was determined using kinase kits (BRAFWT cat. ID: 78316) and (BRAFV600E cat. ID: 48688) were purchased from BPS Biosciences and kinaseGlo Max luminescence kinase assay kit (Promega). ..

    Article Title: Untargeted Diversity-Oriented Synthesis for the Discovery of New Antitumor Agents: An Integrated Approach of Inverse Virtual Screening, Bioinformatics, and Omics for Target Deconvolution
    Article Snippet: .. The B-Raf kinase assay (V600E; BPS Bioscience, USA) was designed to measure B-Raf kinase activity by the use of Kinase-Glo MAX (Promega, USA), which detects ATP residual following the kinase reaction. ..

    Article Title: Investigation into the Use of Encorafenib to Develop Potential PROTACs Directed against BRAF V600E Protein.
    Article Snippet: .. BRAFV600E Inhibition Assay Inhibition of B-RAF (V600E) Kinase activity by synthesized compounds was measured with a B-RAF (V600E) Kinase Assay Kit purchased from BPS Bioscience using Kinase-Glo MAX® (Promega Corporation, Madison, Wisconsin, USA) as detection reagent. ..

    Inhibition:

    Article Title: Investigation into the Use of Encorafenib to Develop Potential PROTACs Directed against BRAF V600E Protein.
    Article Snippet: .. BRAFV600E Inhibition Assay Inhibition of B-RAF (V600E) Kinase activity by synthesized compounds was measured with a B-RAF (V600E) Kinase Assay Kit purchased from BPS Bioscience using Kinase-Glo MAX® (Promega Corporation, Madison, Wisconsin, USA) as detection reagent. ..

    Synthesized:

    Article Title: Investigation into the Use of Encorafenib to Develop Potential PROTACs Directed against BRAF V600E Protein.
    Article Snippet: .. BRAFV600E Inhibition Assay Inhibition of B-RAF (V600E) Kinase activity by synthesized compounds was measured with a B-RAF (V600E) Kinase Assay Kit purchased from BPS Bioscience using Kinase-Glo MAX® (Promega Corporation, Madison, Wisconsin, USA) as detection reagent. ..



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